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A two-sample median test was used to compare medians of CAC progression between the garlic- and placebo-treated groups.

CAC progression was also categorized into three groups (20%) prior to adjustment for age and gender.

It has also been shown to be especially effective in quantifying trends of CAC over time [20].

Received date: September 10, 2015; Accepted date: September 21, 2015; Published date: October 05, 2015 Citation: Hom C, Luo Y, Budoff MJ (2015) The Effects of Aged Garlic Extract on Coronary Artery Calcification Progression. Since AGE has been shown to have several potential anti-atherosclerotic properties, including stimulation of microcirculation in peripheral arteries, it was chosen as the agent of study to evaluate its ability to inhibit progression of coronary atherosclerosis.

Visit for more related articles at Journal of Nutrition & Food Sciences Background: Aged Garlic Extract (AGE) has been shown to lower LDL, reduce the progression of coronary atherosclerosis, improve vascular function, and have a favorable effect on oxidative biomarkers.

These results were supported by another study that found that patients given AGE demonstrated a significant slowing of the accumulation of coronary artery calcification.

The difference in progression was significant, whether measured by absolute plaque volume or percent change.

Progression of calcified lesions in the wall of the coronary artery has been investigated as an active process of atherosclerosis, dependent upon multiple variables [21].

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